Celebrex is used to treat pain, fever, swelling, and tenderness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It only relieves the symptoms of arthiritis and does not prevent the progression of either type of arthritis. It may also be used in patients with familial FAP who have not had their colons removed. It may also be used for the relief of acute pain and the pain of menstrual cramps (primary dysmenorrhea).
Following the dosage instructions of your doctor is the best way to use any medication. If you are unsure or do not remember the instructions then you may read the medicine label for more detailed information.
In case of management of osteoarthritis the ideal dosage is 100 mg twice daily or 200 mg as a single dose.
In case of rheumatoid arthritis the dosage should be 100 or 200 mg twice daily.
For acute pain or menstrual cramps, 00 mg as a single dose on the first day is recommended followed by 200 mg if necessary. After that 200mg twice daily should be consumed as needed.
In case of FAP, the dosage is 400 mg twice daily.
Drug Class and Mechanism
Celebrex is classified as a nonsteroidal anti-inflammatory drug (NSAID). It can be used in the treatment of thritis, pain, menstrual cramps, and colonic polyps. Celecoxib blocks the enzyme that produces Prostaglandins (a chemical that contributes to inflammation of arthritis in turn resulting in pain, fever, swelling and tenderness).
Celecoxib is different from other NSAIDs as it causes relatively less inflammation and ulceration of stomach and its dosage does not cause any effect on the clotting of blood.
Celecoxib is known to prevent the formation and reduce the size of polyps in patients with the genetic disease, familial adenomatous polyposis (FAP). Therefore Celecoxib is used as an adjunctive (secondary) treatment of FAP.
Celecoxib also reduces the cramping and pain during menstrual periods caused due to prostaglandins.
Despite your best attempts at remembering, if you still miss out on a dose, then take it as soon as you remember about it. But keep in mind that you will have to adjust your next dose by spacing it out by 4 to 5 hours. If this is not possible, then the best thing to do would be to skip the missed dose and continue with your normal dosage schedule.
Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects.
Store Celebrex at 25 degrees C (77 degrees F). You may also store it between 15-30 degrees C (59-86 degrees F) for a brief period.
Doctors advise against using Celebrex if you are allergic to any ingredient in it or if you have conditions like
Discuss your past/current medical history in detail with your doctor before beginning treatment with any new medication. If you are undergoing lithium therapy, or using anticoagulant (blood thinner) warfarin (Coumadin) then mention it to your doctor.
Your condition might be monitored or the dosage might be modified to suit you if you are consuming fluconazole, aspirin or other NSAIDs
Celebrex may increase the risk of getting dizziness or drowsiness. This risk of developing stomach ulcers greatly increases if you combine it with more than 3 alcoholic beverages everyday. So please avoid them while using Celebrex. Also, avoid undertaking any tasks which require mental alertness (driving, handling heavy machinery etc).
If you are expecting a child or are planning to have a child in the near future, then consult your doctor before using Celebrex to discuss any possible threats to the unborn baby. It should only be used in pregnant women if the risks are lesser than the potential benefits.
If you are a nursing mother and breast feed your baby, then too, seek consultation before using Celebrex as some drugs are excreted in the breast milk and may enter the baby.
Most medications have some kind of side effects associated with them. The commonest of these side effects are temporary and mild and fade away without any special attention.
These include flatulence or diarrhea; dizziness; headache; or insomnia.
However, in some cases, these mild side effects may persist or become bothersome. In such cases, seek medical attention.
Also, in some rare cases, it may lead to severe side effects whose symptoms can be abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. Some adverse side effects include headache, abdominal pain, dyspepsia, diarrhea, nausea, flatulence and insomnia.
Seek medical attention if you notice any of these symptoms or side effects.
Side effects that are not listed here may also occur.